First “Live Case” Transmission of a PFO Closure Procedure Using the Coherex FlatStent PFO Closure System to be Presented at TCT 2007

Closed circuit satellite broadcast from Germany of this breakthrough procedure is being directed by Principal Investigator, Prof. Horst Sievert, M.D.

SALT LAKE CITY and WASHINGTON, D.C. – October 21, 2007 – Coherex Medical today announced that physicians attending the Cardiovascular Research Foundation’s (CRF) nineteenth annual Transcatheter Cardiovascular Therapeutics (TCT) scientific symposium will have the first opportunity to observe a “live case” PFO closure procedure using the Coherex FlatStent™ PFO Closure System.

The live case is part of the COHEREX-EU CE Mark Study and will be conducted at 9 a.m. (EDT) on Monday, October 22, 2007 at Sankt Katharinen Hospital in Frankfurt, Germany and delivered via closed circuit satellite broadcast in the Main Arena at TCT 2007. Prof. Horst Sievert, M.D. is the Principal Investigator of the COHEREX-EU Study.

“This live case broadcast is a great opportunity for cardiologists to see how the Coherex FlatStent can be used to close a heart defect called a patent foramen ovale (PFO) quickly and easily,” said Richard J. Linder, Coherex president and CEO. “Approximately 25 percent of all adults have a PFO, which may lead to an increased incidence of stroke or migraine. We believe that we have pioneered a new class of stent that will be used in much the same way as existing stents but with one major exception – the Coherex FlatStent is used to close a cardiac structure instead of opening one. We invite all TCT 2007 attendees to join us in the main arena for this broadcast.”

In addition to its first live case transmission, Coherex will hold a special symposium for physicians and medical professionals attending TCT 2007 entitled “The Coherex FlatStent – The Future of PFO Closure.” Preceded by a breakfast starting at 6:30 a.m., the Coherex program will be held from 7 a.m. to 8 a.m. on October 22 in Room 144C in the Washington Convention Center.

The specific schedule for the Coherex program is as follows:

7:00 a.m.     “New Frontiers: Structural Heart Surgery in the Interventional Suite,”
                       Martin B. Leon, M.D. (Columbia University Medical Center and
                       Chairman Emeritus of the Cardiovascular Research Foundation)

7:10 a.m.     “The Coherex FlatStent PFO Closure System: Device Design and
                       Preclinical Testing,” Brian Whisenant, M.D. (Utah Heart Clinic,
                       Salt Lake City and Coherex Medical co-founder)

7:20 a.m.     “Initial Experience with the Coherex FlatStent,”
                       Jonathan M. Tobis, M.D. (UCLA Medical Center)

7:30 a.m.     “Establishing a Migraine PFO Research Program: Real World Issues,”
                       Robert J. Sommer, M.D. (Columbia University Medical Center)

7:40 a.m.     “Optimizing Patient Selection and Clinical Trial Design in Migraine,”
                       Mark Reisman, M.D. (Swedish Heart Institute, Seattle)

7:50 a.m.     “Closing Remarks,” Robert J. Sommer, M.D.
                       (Columbia University Medical Center).
 
TCT 2007 participants interested in attending the Coherex program should contact Phil Carter at 801-231-5297 or pcarter@coherex.com. Interested parties can also visit Coherex Medical at booth #1064 during TCT 2007.

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